iPTMnet Report for Q8IXH7 (NELFCD)
Protein Information
UniProt AC / UniProt ID | Q8IXH7 / NELFD_HUMAN |
Protein Name | Negative elongation factor C/D |
Gene Name | Name: NELFCD Synonyms:NELFD,TH1,TH1L;ORFNames:HSPC130; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IXH7 |
PRO Name | negative elongation factor C/D (human) |
Definition | A negative elongation factor C/D that is encoded in the genome of human. |
Short Label | hNELFCD |
Category | organism-gene |
Q8IXH7 (NELFCD) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
T53 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y56 | Phosphorylation | score1 | PhosphoSitePlus | |||
T65 | Phosphorylation | score1 | PhosphoSitePlus | |||
K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
S121 | Phosphorylation | score1 | PhosphoSitePlus | |||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
K272 | Ubiquitination | score1 | PhosphoSitePlus | |||
T280 | Phosphorylation | score1 | PhosphoSitePlus | |||
T285 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y289 | Phosphorylation | score1 | PhosphoSitePlus | |||
R291 | Methylation | score1 | PhosphoSitePlus | |||
S301 | Phosphorylation | score1 | PhosphoSitePlus | |||
K372 | Acetylation | score1 | PhosphoSitePlus | |||
K374 | Acetylation | score1 | PhosphoSitePlus | |||
K380 | Acetylation | score1 | PhosphoSitePlus | |||
K380 | Ubiquitination | score1 | PhosphoSitePlus | |||
K384 | Ubiquitination | score1 | PhosphoSitePlus | |||
K388 | Ubiquitination | score1 | PhosphoSitePlus | |||
T392 | Phosphorylation | score1 | PhosphoSitePlus | |||
K567 | Sumoylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y6 | Phosphorylation | P12931 (SRC) | score2 | PhosphoSitePlus | 22238675 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T53 | P53 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S121 | R121 | Biomuta | DOID:1909 / melanoma [ tcga ] | |
T280 | I280 | Biomuta | DOID:1324 / lung cancer [ tcga ] | |
K567 | N567 | Biomuta | DOID:1612 / breast cancer [ cosmic ] |