Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IXH7 / NELFD_HUMAN
Protein Name Negative elongation factor C/D
Gene Name Name: NELFCD
Synonyms:NELFD,TH1,TH1L;ORFNames:HSPC130;
Organism Homo sapiens (Human)

PRO ID PR:Q8IXH7
DAG View
PRO Name negative elongation factor C/D (human)
Definition A negative elongation factor C/D that is encoded in the genome of human.
Short Label hNELFCD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IXH7 (NELFCD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S34 Phosphorylation PhosphoSitePlus
T53 Phosphorylation PhosphoSitePlus
Y56 Phosphorylation PhosphoSitePlus
T65 Phosphorylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
T285 Phosphorylation PhosphoSitePlus
Y289 Phosphorylation PhosphoSitePlus
R291 Methylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
K372 Acetylation PhosphoSitePlus
K374 Acetylation PhosphoSitePlus
K380 Acetylation PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
T392 Phosphorylation PhosphoSitePlus
K567 Sumoylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y6 Phosphorylation P12931 (SRC) PhosphoSitePlus 22238675


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T53 P53 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S121 R121 Biomuta DOID:1909 / melanoma [ tcga ]
T280 I280 Biomuta DOID:1324 / lung cancer [ tcga ]
K567 N567 Biomuta DOID:1612 / breast cancer [ cosmic ]