iPTMnet Report for Q8IX21 (SLF2)
Protein Information
UniProt AC / UniProt ID | Q8IX21 / SLF2_HUMAN |
Protein Name | SMC5-SMC6 complex localization factor protein 2 |
Gene Name | Name: SLF2 Synonyms:C10orf6,FAM178A; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IX21 |
PRO Name | SMC5-SMC6 complex localization factor protein 2 (human) |
Definition | An SMC5-SMC6 complex localization factor protein 2 that is encoded in the genome of human. |
Short Label | hSLF2 |
Category | organism-gene |
Q8IX21 (SLF2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
S50 | Phosphorylation | score1 | PhosphoSitePlus | |||
S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y76 | Phosphorylation | score1 | PhosphoSitePlus | |||
S82 | Phosphorylation | score1 | PhosphoSitePlus | |||
S109 | Phosphorylation | score1 | PhosphoSitePlus | |||
S170 | Phosphorylation | score1 | PhosphoSitePlus | |||
S176 | Phosphorylation | score1 | PhosphoSitePlus | |||
T193 | Phosphorylation | score1 | PhosphoSitePlus | |||
S197 | Phosphorylation | score1 | PhosphoSitePlus | |||
S221 | Phosphorylation | score1 | PhosphoSitePlus | |||
S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
S230 | Phosphorylation | score1 | PhosphoSitePlus | |||
S317 | Phosphorylation | score1 | PhosphoSitePlus | |||
T323 | Phosphorylation | score1 | PhosphoSitePlus | |||
S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
K394 | Ubiquitination | score1 | PhosphoSitePlus | |||
T400 | Phosphorylation | score1 | PhosphoSitePlus | |||
S403 | Phosphorylation | score1 | PhosphoSitePlus | |||
S404 | Phosphorylation | score1 | PhosphoSitePlus | |||
S444 | Phosphorylation | score1 | PhosphoSitePlus | |||
S454 | Phosphorylation | score1 | PhosphoSitePlus | |||
S477 | Phosphorylation | score1 | PhosphoSitePlus | |||
S481 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S484 | Phosphorylation | score1 | PhosphoSitePlus | |||
S508 | Phosphorylation | score1 | PhosphoSitePlus | |||
S512 | Phosphorylation | score1 | PhosphoSitePlus | |||
S515 | Phosphorylation | score1 | PhosphoSitePlus | |||
S518 | Phosphorylation | score1 | PhosphoSitePlus | |||
T551 | Phosphorylation | score1 | PhosphoSitePlus | |||
S555 | Phosphorylation | score1 | PhosphoSitePlus | |||
S568 | Phosphorylation | score1 | PhosphoSitePlus | |||
S573 | Phosphorylation | score1 | PhosphoSitePlus | |||
S578 | Phosphorylation | score1 | PhosphoSitePlus | |||
S603 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S607 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S614 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
K647 | Ubiquitination | score1 | PhosphoSitePlus | |||
S653 | Phosphorylation | score1 | PhosphoSitePlus | |||
S654 | Phosphorylation | score1 | PhosphoSitePlus | |||
T657 | Phosphorylation | score1 | PhosphoSitePlus | |||
T679 | Phosphorylation | score1 | PhosphoSitePlus | |||
K687 | Ubiquitination | score1 | PhosphoSitePlus | |||
S701 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S710 | Phosphorylation | score1 | PhosphoSitePlus | |||
T711 | Phosphorylation | score1 | PhosphoSitePlus | |||
K774 | Ubiquitination | score1 | PhosphoSitePlus | |||
K903 | Ubiquitination | score1 | PhosphoSitePlus | |||
S948 | O-Glycosylation | score1 | GlyGen | 30379171, 34019948 | ||
S1018 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1024 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T193 | A193 | Biomuta | DOID:4362 / cervical cancer [ icgc ] | |
S221 | R221 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S515 | C515 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S568 | G568 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S573 | T573 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S603 | I603 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K687 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T711 | P711 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K1024 | N1024 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |