iPTMnet Report for Q8IX18 (DHX40)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IX18 / DHX40_HUMAN
Protein Name Probable ATP-dependent RNA helicase DHX40
Gene Name Name: DHX40
Synonyms:DDX40;ORFNames:ARG147;
Organism Homo sapiens (Human)

PRO ID PR:Q8IX18
DAG View
PRO Name probable ATP-dependent RNA helicase DHX40 (human)
Definition A probable ATP-dependent RNA helicase DHX40 that is encoded in the genome of human.
Short Label hDHX40
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IX18 (DHX40) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R3 Methylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
T50 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
T78 Phosphorylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
T84 Phosphorylation PhosphoSitePlus
Y91 Phosphorylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
K387 Ubiquitination PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K615 Ubiquitination PhosphoSitePlus
S648 Phosphorylation PhosphoSitePlus
C685 Methylation IEDB 31844290
K730 Acetylation PhosphoSitePlus
K733 Acetylation PhosphoSitePlus
K743 Acetylation PhosphoSitePlus
T768 Phosphorylation PhosphoSitePlus
S772 Phosphorylation PhosphoSitePlus
T774 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K61 N61 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K108 E108 Biomuta DOID:3571 / liver cancer [ cosmic ]
S168 R168 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic, icgc ]
K733 N733 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S772 N772 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
T774 I774 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]