Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWY4 / SCUB1_HUMAN
Protein Name Signal peptide, CUB and EGF-like domain-containing protein 1 precursor
Gene Name Name: SCUBE1
Organism Homo sapiens (Human)

PRO ID PR:Q8IWY4
DAG View
PRO Name signal peptide, CUB and EGF-like domain-containing protein 1 (human)
Definition A signal peptide, CUB and EGF-like domain-containing protein 1 that is encoded in the genome of human.
Short Label hSCUBE1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWY4 (SCUBE1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T18 Phosphorylation HPRD   PhosphoSitePlus 18691976
Y312 Phosphorylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
T482 Phosphorylation PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
T564 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y312 * Biomuta DOID:1612 / breast cancer [ cosmic ]
T482 P482 Biomuta DOID:10534 / stomach cancer [ cosmic ]