iPTMnet Report for Q8IWX7 (UNC45B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWX7 / UN45B_HUMAN
Protein Name Protein unc-45 homolog B
Gene Name Name: UNC45B
Synonyms:CMYA4,UNC45;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWX7
DAG View
PRO Name protein unc-45 homolog B (human)
Definition A protein unc-45 homolog B that is encoded in the genome of human.
Short Label hUNC45B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWX7 (UNC45B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T44 Phosphorylation PhosphoSitePlus
Y46 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
Y81 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
T134 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
K289 Acetylation PhosphoSitePlus
K471 Acetylation PhosphoSitePlus
T495 Phosphorylation PhosphoSitePlus
S567 Phosphorylation phospho.ELM 17081983
S602 Phosphorylation PhosphoSitePlus
T669 Phosphorylation PhosphoSitePlus
Y717 Phosphorylation PhosphoSitePlus
K906 Acetylation PhosphoSitePlus
K907 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y46 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S75 L75 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T134 I134 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S567 R567 Biomuta DOID:3571 / liver cancer [ cosmic ]