iPTMnet Report for Q8IWW8 (ADHFE1)
Protein Information
UniProt AC / UniProt ID | Q8IWW8 / HOT_HUMAN |
Protein Name | Hydroxyacid-oxoacid transhydrogenase, mitochondrial precursor |
Gene Name | Name: ADHFE1 ORFNames:HMFT2263; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IWW8 |
PRO Name | hydroxyacid-oxoacid transhydrogenase, mitochondrial (human) |
Definition | A hydroxyacid-oxoacid transhydrogenase, mitochondrial that is encoded in the genome of human. |
Short Label | hADHFE1 |
Category | organism-gene |
Q8IWW8 (ADHFE1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K82 | Acetylation | score1 | PhosphoSitePlus | |||
S175 | Phosphorylation | score1 | PhosphoSitePlus | |||
T219 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y334 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y343 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y334 | C334 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |