Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8IWW8 / HOT_HUMAN
Protein Name Hydroxyacid-oxoacid transhydrogenase, mitochondrial precursor
Gene Name Name: ADHFE1
Organism Homo sapiens (Human)

DAG View
PRO Name hydroxyacid-oxoacid transhydrogenase, mitochondrial (human)
Definition A hydroxyacid-oxoacid transhydrogenase, mitochondrial that is encoded in the genome of human.
Short Label hADHFE1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8IWW8 (ADHFE1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K82 Acetylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y334 C334 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]