iPTMnet Report for Q8IWV2 (CNTN4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWV2 / CNTN4_HUMAN
Protein Name Contactin-4 precursor
Gene Name Name: CNTN4
Organism Homo sapiens (Human)

PRO ID PR:Q8IWV2
DAG View
PRO Name contactin-4 (human)
Definition A contactin-4 that is encoded in the genome of human.
Short Label hCNTN4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWV2 (CNTN4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N65 N-Glycosylation GlyGen   UniProt 16335952, 29391424, 24190977
T131 Phosphorylation PhosphoSitePlus
T176 Phosphorylation PhosphoSitePlus
Y180 Phosphorylation PhosphoSitePlus
N191 N-Glycosylation GlyGen 24190977
Y223 Phosphorylation PhosphoSitePlus
N466 N-Glycosylation GlyGen 29391424
S474 Phosphorylation PhosphoSitePlus
T476 Phosphorylation PhosphoSitePlus
S487 Phosphorylation PhosphoSitePlus
Y670 Phosphorylation IEDB 35494241
T694 Phosphorylation IEDB 35494241
N705 N-Glycosylation GlyGen 29391424
N764 N-Glycosylation GlyGen 29671580, 29391424
T855 Phosphorylation PhosphoSitePlus
N858 N-Glycosylation GlyGen 29741879, 29671580, 29391424
N929 N-Glycosylation GlyGen 29391424, 24190977
N1006 N-Glycosylation GlyGen 29391424
T1015 Phosphorylation PhosphoSitePlus
T1021 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N764 N-Glycosylation PRO 29671580
T855 Phosphorylation HPRD 19651622
N858 N-Glycosylation PRO 29671580
T862 Phosphorylation HPRD 19651622
Site PTM Type PTM Enzyme Score Source PMID
T527 Phosphorylation HPRD 19651622
T534 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y223 H223 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S474 I474 Biomuta DOID:1324 / lung cancer [ cosmic ]
S487 G487 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N858 T858 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T1015 I1015 Biomuta DOID:363 / uterine cancer [ icgc ]
T1021 I1021 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T1021 S1021 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]