iPTMnet Report for Q8IWU6 (SULF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWU6 / SULF1_HUMAN
Protein Name Extracellular sulfatase Sulf-1 precursor
Gene Name Name: SULF1
Synonyms:KIAA1077;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWU6
DAG View
PRO Name extracellular sulfatase Sulf-1 (human)
Definition An extracellular sulfatase Sulf-1 that is encoded in the genome of human.
Short Label hSULF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWU6 (SULF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T24 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
T96 Phosphorylation PhosphoSitePlus
N111 N-Glycosylation GlyGen 29741879
N131 N-Glycosylation GlyGen 29741879
N170 N-Glycosylation GlyGen 29741879
N197 N-Glycosylation GlyGen   UniProt 29741879, 19159218
T285 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
T367 Phosphorylation PhosphoSitePlus
K417 Acetylation PhosphoSitePlus
Y438 Phosphorylation PhosphoSitePlus
N623 N-Glycosylation GlyGen 29741879
K648 Ubiquitination PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T285 N285 Biomuta DOID:1612 / breast cancer [ cosmic ]
T367 K367 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T367 M367 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y438 S438 Biomuta DOID:4159 / skin cancer [ cosmic ]