iPTMnet Report for Q8IWU5 (SULF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWU5 / SULF2_HUMAN
Protein Name Extracellular sulfatase Sulf-2 precursor
Gene Name Name: SULF2
Synonyms:KIAA1247;ORFNames:UNQ559/PRO1120;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWU5
DAG View
PRO Name extracellular sulfatase Sulf-2 (human)
Definition An extracellular sulfatase Sulf-2 that is encoded in the genome of human.
Short Label hSULF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWU5 (SULF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation PhosphoSitePlus
N112 N-Glycosylation GlyGen 23090970, 29741879, 32125861, ...24190977
Y130 Phosphorylation PhosphoSitePlus
N132 N-Glycosylation GlyGen 23090970, 29741879, 24190977
Y148 Phosphorylation PhosphoSitePlus
N149 N-Glycosylation GlyGen 23090970, 30237853, 24190977
Y152 Phosphorylation PhosphoSitePlus
N171 N-Glycosylation GlyGen 23090970, 24190977
N198 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
N241 N-Glycosylation GlyGen 23090970, 24190977
K269 Acetylation PhosphoSitePlus
K282 Acetylation PhosphoSitePlus
Y497 Phosphorylation PhosphoSitePlus
S583 O-Glycosylation GlyGen   UniProt 35294879
N608 N-Glycosylation GlyGen 23090970
K694 Ubiquitination PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus
S838 Phosphorylation PhosphoSitePlus
K859 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N241 K241 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K269 N269 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y497 * Biomuta DOID:1324 / lung cancer [ cosmic ]