iPTMnet Report for Q8IWT3 (CUL9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWT3 / CUL9_HUMAN
Protein Name Cullin-9
Gene Name Name: CUL9
Synonyms:H7AP1,KIAA0708,PARC;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWT3
DAG View
PRO Name cullin-9 (human)
Definition A cullin-9 that is encoded in the genome of human.
Short Label hCUL9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWT3 (CUL9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S43 Phosphorylation PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
T355 Phosphorylation PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus
S589 Phosphorylation PhosphoSitePlus
T591 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus
K627 Ubiquitination PhosphoSitePlus
T760 Phosphorylation PhosphoSitePlus
S930 Phosphorylation PhosphoSitePlus
T938 Phosphorylation PhosphoSitePlus
S947 Phosphorylation PhosphoSitePlus
S976 Phosphorylation PhosphoSitePlus   UniProt 23186163
K986 Ubiquitination PhosphoSitePlus
T992 Phosphorylation PhosphoSitePlus
K1086 Ubiquitination PhosphoSitePlus
K1090 Ubiquitination PhosphoSitePlus
C1108 Methylation IEDB 31844290
K1172 Ubiquitination PhosphoSitePlus
K1184 Ubiquitination PhosphoSitePlus
K1299 Ubiquitination PhosphoSitePlus
S1408 Phosphorylation PhosphoSitePlus
S1413 Phosphorylation PhosphoSitePlus
S1417 Phosphorylation PhosphoSitePlus
S1448 Phosphorylation PhosphoSitePlus
S1457 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1503 Ubiquitination PhosphoSitePlus
K1657 Ubiquitination PhosphoSitePlus
K1668 Ubiquitination PhosphoSitePlus
K1718 Ubiquitination PhosphoSitePlus
K1859 Ubiquitination PhosphoSitePlus
K1881 Sumoylation PhosphoSitePlus
K1881 Ubiquitination PhosphoSitePlus
K2007 Ubiquitination PhosphoSitePlus
K2144 Ubiquitination PhosphoSitePlus
K2230 Ubiquitination PhosphoSitePlus
S2238 Phosphorylation PhosphoSitePlus
K2245 Ubiquitination PhosphoSitePlus
K2285 Ubiquitination PhosphoSitePlus
S2318 Phosphorylation PhosphoSitePlus
S2436 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S947 Phosphorylation HPRD 18691976
S2436 Phosphorylation HPRD 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K46 T46 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S316 N316 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S947 P947 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S976 R976 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]