iPTMnet Report for Q8IWT1 (SCN4B)
Protein Information
| UniProt AC / UniProt ID | Q8IWT1 / SCN4B_HUMAN |
| Protein Name | Sodium channel subunit beta-4 precursor |
| Gene Name | Name: SCN4B |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8IWT1 |
| PRO Name | sodium channel subunit beta-4 (human) |
| Definition | A sodium channel subunit beta-4 that is encoded in the genome of human. |
| Short Label | hSCN4B |
| Category | organism-gene |
Q8IWT1 (SCN4B) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T69 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y70 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S73 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K92 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S73 | I73 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S73 | G73 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K92 | R92 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
DAG View