iPTMnet Report for Q8IWR1 (TRIM59)
Protein Information
| UniProt AC / UniProt ID | Q8IWR1 / TRI59_HUMAN |
| Protein Name | Tripartite motif-containing protein 59 |
| Gene Name | Name: TRIM59 Synonyms:RNF104,TRIM57,TSBF1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8IWR1 |
| PRO Name | tripartite motif-containing protein 59 (human) |
| Definition | A tripartite motif-containing protein 59 that is encoded in the genome of human. |
| Short Label | hTRIM59 |
| Category | organism-gene |
Q8IWR1 (TRIM59) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T144 | Phosphorylation | score0 | RLIMS-P | 31488827 | ||
| K176 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S246 | Phosphorylation | score0 | RLIMS-P | 31488827 | ||
| K253 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y278 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K298 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S308 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 31488827 | ||
| K310 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S308 | F308 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S308 | A308 | Biomuta | [ cosmic ] |
DAG View