iPTMnet Report for Q8IWQ3 (BRSK2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWQ3 / BRSK2_HUMAN
Protein Name Serine/threonine-protein kinase BRSK2
Gene Name Name: BRSK2
Synonyms:C11orf7,PEN11B,SADA,STK29;ORFNames:HUSSY-12;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWQ3
DAG View
PRO Name serine/threonine-protein kinase BRSK2 (human)
Definition A serine/threonine-protein kinase BRSK2 that is encoded in the genome of human.
Short Label hBRSK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWQ3 (BRSK2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y15 Phosphorylation PhosphoSitePlus
K23 Sumoylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
T174 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 22798068, 14976552, 18339622, ...16870137, 32985588, 17482548
T174 Phosphorylation Q15831 (STK11) PhosphoSitePlus   Signor 14976552
T174 Phosphorylation Q8IWQ3 (BRSK2) neXtProt 22798068
T260 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 16870137
T260 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 16870137
Y270 Phosphorylation IEDB 35494241
S294 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus   UniProt 19369195
S382 Phosphorylation PhosphoSitePlus   UniProt 19369195, 19690332
S393 Phosphorylation PhosphoSitePlus   UniProt 19369195, 19690332
R409 Methylation PhosphoSitePlus
S410 Phosphorylation PhosphoSitePlus
R411 Methylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus   UniProt 19690332
A416 Phosphorylation UniProt 19369195
S423 Phosphorylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
T431 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
R437 Methylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
T443 Phosphorylation PhosphoSitePlus
T459 Phosphorylation PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
S489 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S506 Phosphorylation PhosphoSitePlus
T509 Phosphorylation PhosphoSitePlus   UniProt 19690332
S512 Phosphorylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
S520 O-Glycosylation GlyGen 30379171
S520 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S382 Phosphorylation HPRD 19413330
S393 Phosphorylation HPRD 19413330
S423 Phosphorylation HPRD 19413330
S489 Phosphorylation HPRD 18669648
K661 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S416 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus


Q8IWQ3 (BRSK2) as PTM Enzyme



Substrate Site Score Source PMID
P10636 (MAPT) T529 neXtProt 21985311, 15705853, 17482548
P10636 (MAPT) S579 neXtProt 21985311, 15705853, 17482548
P30291 (WEE1) S642 HPRD   neXtProt 15150265, 20026642
P30307-1 (CDC25C) S216 HPRD 9543386, 10557092, 9278512, ...11333986, 11551930, 20068231
Q00536 (CDK16) S12 neXtProt   PhosphoSitePlus 22798068
Q13131 (PRKAA1) T183 PhosphoSitePlus   Signor 21918180, 18854318
Q13153 (PAK1) T423 neXtProt 22669945
Q8IWQ3 (BRSK2) T174 neXtProt 22798068