Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWL3 / HSC20_HUMAN
Protein Name Iron-sulfur cluster co-chaperone protein HscB precursor
Gene Name Name: HSCB
Synonyms:DNAJC20,HSC20;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWL3
DAG View
PRO Name iron-sulfur cluster co-chaperone protein HscB (human)
Definition An iron-sulfur cluster co-chaperone protein HscB that is encoded in the genome of human.
Short Label hHSCB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWL3 (HSCB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S82 Phosphorylation PhosphoSitePlus
T87 Phosphorylation PhosphoSitePlus
Y94 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S82 F82 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T87 I87 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K119 R119 Biomuta DOID:1324 / lung cancer [ cosmic ]
K212 E212 Biomuta DOID:1324 / lung cancer [ tcga ]
K212 T212 Biomuta DOID:11934 / head and neck cancer [ tcga ]