iPTMnet Report for Q8IWL3 (HSCB)
Protein Information
| UniProt AC / UniProt ID | Q8IWL3 / HSC20_HUMAN |
| Protein Name | Iron-sulfur cluster co-chaperone protein HscB |
| Gene Name | Name: HSCB Synonyms:DNAJC20,HSC20; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8IWL3 |
| PRO Name | iron-sulfur cluster co-chaperone protein HscB (human) |
| Definition | An iron-sulfur cluster co-chaperone protein HscB that is encoded in the genome of human. |
| Short Label | hHSCB |
| Category | organism-gene |
DAG ViewQ8IWL3 (HSCB) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S82 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y94 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S107 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S201 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K212 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S82 | F82 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T87 | I87 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K119 | R119 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K212 | E212 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K212 | T212 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |
