iPTMnet Report for Q8IWK6 (ADGRA3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWK6 / AGRA3_HUMAN
Protein Name Adhesion G protein-coupled receptor A3 precursor
Gene Name Name: ADGRA3
Synonyms:GPR125;ORFNames:UNQ556/PRO1113;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWK6
DAG View
PRO Name adhesion G protein-coupled receptor A3 (human)
Definition An adhesion G protein-coupled receptor A3 that is encoded in the genome of human.
Short Label hADGRA3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWK6 (ADGRA3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T208 Phosphorylation phospho.ELM 17081983
T334 Phosphorylation PhosphoSitePlus
T336 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
N592 N-Glycosylation GlyGen 23090970, 24190977
S632 Phosphorylation PhosphoSitePlus
K635 Ubiquitination PhosphoSitePlus
Y878 Phosphorylation PhosphoSitePlus
Y950 Phosphorylation PhosphoSitePlus
S1097 Phosphorylation PhosphoSitePlus
T1099 Phosphorylation PhosphoSitePlus
S1102 Phosphorylation PhosphoSitePlus
Y1224 Phosphorylation PhosphoSitePlus
S1240 Phosphorylation PhosphoSitePlus
K1248 Ubiquitination PhosphoSitePlus
S1250 Phosphorylation PhosphoSitePlus
K1316 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T208 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T208 M208 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T334 M334 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T336 A336 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y878 H878 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1240 N1240 Biomuta DOID:363 / uterine cancer [ icgc ]
K1316 N1316 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K1316 E1316 Biomuta DOID:4159 / skin cancer [ cosmic ]