Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWI9 / MGAP_HUMAN
Protein Name MAX gene-associated protein
Gene Name Name: MGA
Synonyms:KIAA0518,MAD5;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWI9
DAG View
PRO Name MAX gene-associated protein (human)
Definition A MAX gene-associated protein that is encoded in the genome of human.
Short Label hMGA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWI9 (MGA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S55 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
Y107 Phosphorylation PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
Y121 Phosphorylation PhosphoSitePlus
Y135 Phosphorylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
K382 Sumoylation PhosphoSitePlus
T407 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
K460 Sumoylation PhosphoSitePlus
Y470 Phosphorylation PhosphoSitePlus
T477 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus   UniProt 20068231
K547 Ubiquitination PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus
K570 Sumoylation PhosphoSitePlus
K570 Ubiquitination PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus   UniProt 23186163
K613 Ubiquitination PhosphoSitePlus
K619 Ubiquitination PhosphoSitePlus
K624 Ubiquitination PhosphoSitePlus
K634 Ubiquitination PhosphoSitePlus
T642 Phosphorylation PhosphoSitePlus
S645 Phosphorylation PhosphoSitePlus   UniProt 19690332
S648 Phosphorylation PhosphoSitePlus
T649 Phosphorylation PhosphoSitePlus
K654 Sumoylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
K708 Ubiquitination PhosphoSitePlus
K715 Ubiquitination PhosphoSitePlus
K720 Ubiquitination PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
S772 Phosphorylation PhosphoSitePlus
K791 Ubiquitination PhosphoSitePlus
K798 Acetylation PhosphoSitePlus
K798 Ubiquitination PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
K826 Ubiquitination PhosphoSitePlus
S851 Phosphorylation PhosphoSitePlus   UniProt 23186163
S876 Phosphorylation PhosphoSitePlus
S879 Phosphorylation PhosphoSitePlus
Y915 Phosphorylation PhosphoSitePlus
Y921 Phosphorylation PhosphoSitePlus
S924 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
K928 Methylation PhosphoSitePlus
K928 Sumoylation PhosphoSitePlus
K937 Methylation PhosphoSitePlus
K937 Ubiquitination PhosphoSitePlus
K990 Ubiquitination PhosphoSitePlus
T1113 Phosphorylation PhosphoSitePlus
K1140 Ubiquitination PhosphoSitePlus
K1162 Sumoylation PhosphoSitePlus
S1195 Phosphorylation PhosphoSitePlus
K1201 Ubiquitination PhosphoSitePlus
K1207 Ubiquitination PhosphoSitePlus
S1208 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T1213 Phosphorylation PhosphoSitePlus
K1291 Ubiquitination PhosphoSitePlus
K1303 Ubiquitination PhosphoSitePlus
K1307 Ubiquitination PhosphoSitePlus
K1310 Ubiquitination PhosphoSitePlus
S1328 Phosphorylation PhosphoSitePlus
K1334 Ubiquitination PhosphoSitePlus
S1371 Phosphorylation PhosphoSitePlus
S1378 Phosphorylation PhosphoSitePlus
K1386 Ubiquitination PhosphoSitePlus
S1412 Phosphorylation PhosphoSitePlus
S1414 Phosphorylation PhosphoSitePlus
T1416 Phosphorylation PhosphoSitePlus
S1422 Phosphorylation PhosphoSitePlus
S1430 Phosphorylation PhosphoSitePlus   UniProt 20068231
S1439 Phosphorylation PhosphoSitePlus
K1448 Ubiquitination PhosphoSitePlus
S1457 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K1461 Ubiquitination PhosphoSitePlus
S1470 Phosphorylation PhosphoSitePlus
S1481 Phosphorylation PhosphoSitePlus
S1488 Phosphorylation PhosphoSitePlus
T1493 Phosphorylation PhosphoSitePlus
S1499 Phosphorylation PhosphoSitePlus
K1502 Ubiquitination PhosphoSitePlus
S1506 Phosphorylation PhosphoSitePlus
K1516 Ubiquitination PhosphoSitePlus
K1519 Acetylation PhosphoSitePlus
K1525 Acetylation PhosphoSitePlus
S1533 Phosphorylation PhosphoSitePlus
K1552 Ubiquitination PhosphoSitePlus
S1557 O-Glycosylation PhosphoSitePlus
T1558 Phosphorylation PhosphoSitePlus
S1569 Phosphorylation PhosphoSitePlus
S1573 Phosphorylation PhosphoSitePlus
T1579 Phosphorylation PhosphoSitePlus
T1633 Phosphorylation PhosphoSitePlus
T1668 Phosphorylation PhosphoSitePlus
R1761 Methylation PhosphoSitePlus
R1818 Methylation PhosphoSitePlus
S1820 Phosphorylation PhosphoSitePlus
T1822 Phosphorylation PhosphoSitePlus
S1905 Phosphorylation PhosphoSitePlus
S1914 Phosphorylation PhosphoSitePlus
K1915 Ubiquitination PhosphoSitePlus
T1916 Phosphorylation PhosphoSitePlus
K1985 Sumoylation PhosphoSitePlus
K1992 Ubiquitination PhosphoSitePlus
S1996 Phosphorylation PhosphoSitePlus
S2024 Phosphorylation PhosphoSitePlus
K2113 Sumoylation PhosphoSitePlus
S2127 Phosphorylation PhosphoSitePlus
K2135 Sumoylation PhosphoSitePlus
S2143 Phosphorylation PhosphoSitePlus
S2166 Phosphorylation PhosphoSitePlus
T2183 Phosphorylation PhosphoSitePlus
K2238 Sumoylation PhosphoSitePlus
S2243 Phosphorylation PhosphoSitePlus
S2248 Phosphorylation PhosphoSitePlus
R2265 Methylation PhosphoSitePlus   UniProt 24129315
K2284 Sumoylation PhosphoSitePlus
S2376 Phosphorylation PhosphoSitePlus
K2378 Ubiquitination PhosphoSitePlus
K2404 Ubiquitination PhosphoSitePlus
K2406 Acetylation PhosphoSitePlus
K2406 Sumoylation PhosphoSitePlus
K2406 Ubiquitination PhosphoSitePlus
K2413 Ubiquitination PhosphoSitePlus
Y2423 Phosphorylation PhosphoSitePlus
Y2424 Phosphorylation PhosphoSitePlus
K2445 Ubiquitination PhosphoSitePlus
T2449 Phosphorylation PhosphoSitePlus
K2460 Ubiquitination PhosphoSitePlus
K2480 Ubiquitination PhosphoSitePlus
K2485 Ubiquitination PhosphoSitePlus
S2500 Phosphorylation PhosphoSitePlus
K2513 Ubiquitination PhosphoSitePlus
K2520 Ubiquitination PhosphoSitePlus
S2535 Phosphorylation PhosphoSitePlus
S2541 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S2574 Phosphorylation PhosphoSitePlus
S2585 Phosphorylation PhosphoSitePlus
T2599 Phosphorylation PhosphoSitePlus
S2620 Phosphorylation PhosphoSitePlus
T2655 Phosphorylation PhosphoSitePlus
K2698 Acetylation PhosphoSitePlus
K2698 Ubiquitination PhosphoSitePlus
Y2727 Phosphorylation PhosphoSitePlus
S2734 Phosphorylation PhosphoSitePlus
K2738 Ubiquitination PhosphoSitePlus
K2745 Ubiquitination PhosphoSitePlus
K2746 Ubiquitination PhosphoSitePlus
K2777 Acetylation PhosphoSitePlus
K2777 Ubiquitination PhosphoSitePlus
S2787 Phosphorylation PhosphoSitePlus
K2866 Ubiquitination PhosphoSitePlus
K2885 Ubiquitination PhosphoSitePlus
S2898 Phosphorylation PhosphoSitePlus
S2910 Phosphorylation PhosphoSitePlus   UniProt 19690332
S2921 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S2962 Phosphorylation PhosphoSitePlus
S2963 Phosphorylation PhosphoSitePlus
T2966 Phosphorylation PhosphoSitePlus
S2978 Phosphorylation PhosphoSitePlus   UniProt 23186163
S3007 Phosphorylation PhosphoSitePlus
S3059 Phosphorylation PhosphoSitePlus
K3065 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T407 Phosphorylation HPRD 18452278
Y414 Phosphorylation HPRD 18452278
S415 Phosphorylation HPRD 18452278
S417 Phosphorylation HPRD 18452278
S448 Phosphorylation HPRD 19413330
S449 Phosphorylation HPRD 19413330, 18669648
S451 Phosphorylation HPRD 20068231
S534 Phosphorylation HPRD 20068231
S607 Phosphorylation HPRD 19413330, 19664995
S917 Phosphorylation HPRD 20068231
S924 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20058876, 20068231
S1195 Phosphorylation HPRD 20068231
T1204 Phosphorylation HPRD 20068231
S1208 Phosphorylation HPRD 18669648, 20068231
S1412 Phosphorylation HPRD 18452278
T1416 Phosphorylation HPRD 18452278
S1422 Phosphorylation HPRD 18452278
S1430 Phosphorylation HPRD 19651622, 20068231
S1457 Phosphorylation HPRD 18669648, 20068231
S1542 Phosphorylation PhosphoSitePlus
R1552 Methylation PhosphoSitePlus
S1562 Phosphorylation PhosphoSitePlus
R1566 Methylation PhosphoSitePlus
R1577 Methylation PhosphoSitePlus
S1815 Phosphorylation HPRD 19651622, 18452278
S2291 Phosphorylation HPRD 18452278
S2332 Phosphorylation HPRD 20068231, 18452278
S2689 Phosphorylation HPRD 18669648, 18452278
S2701 Phosphorylation HPRD 18452278
S2712 Phosphorylation HPRD 19413330, 19651622
S2850 Phosphorylation HPRD 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y200 S200 Biomuta DOID:3070 / malignant glioma [ tcga ]
S359 I359 Biomuta DOID:3571 / liver cancer [ icgc ]
S360 I360 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S369 P369 Biomuta DOID:1324 / lung cancer [ cosmic ]
S572 L572 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ] DOID:11054 / urinary bladder cancer [ tcga ]
S607 F607 Biomuta DOID:1909 / melanoma [ tcga ]
K624 * Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S645 R645 Biomuta DOID:2394 / ovarian cancer [ icgc, tcga ] DOID:2994 / germ cell cancer [ cosmic ]
K654 N654 Biomuta DOID:3571 / liver cancer [ icgc ]
S704 P704 Biomuta DOID:363 / uterine cancer [ tcga ]
K708 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S736 * Biomuta DOID:9256 / colorectal cancer [ icgc ]
K937 M937 Biomuta DOID:5041 / esophageal cancer [ tcga ]
K1307 * Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K1334 Q1334 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1378 Y1378 Biomuta DOID:363 / uterine cancer [ tcga ]
K1386 N1386 Biomuta DOID:3571 / liver cancer [ icgc ]
S1422 F1422 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1506 Y1506 Biomuta DOID:4362 / cervical cancer [ tcga ]
K1552 N1552 Biomuta DOID:3571 / liver cancer [ icgc ]
T1668 I1668 Biomuta DOID:363 / uterine cancer [ tcga ]
R1761 * Biomuta DOID:5041 / esophageal cancer [ icgc ]
S2921 I2921 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]