iPTMnet Report for Q8IWF2 (FOXRED2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWF2 / FXRD2_HUMAN
Protein Name FAD-dependent oxidoreductase domain-containing protein 2 precursor
Gene Name Name: FOXRED2
Synonyms:ERFAD;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWF2
DAG View
PRO Name FAD-dependent oxidoreductase domain-containing protein 2 (human)
Definition An FAD-dependent oxidoreductase domain-containing protein 2 that is encoded in the genome of human.
Short Label hFOXRED2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWF2 (FOXRED2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K77 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
Y118 Phosphorylation PhosphoSitePlus
N143 N-Glycosylation GlyGen   UniProt 19159218, 24190977
K153 Ubiquitination PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
C601 Methylation IEDB 31844290
K610 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K83 N83 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K508 R508 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K610 * Biomuta DOID:1324 / lung cancer [ cosmic ]