iPTMnet Report for Q8IWB7 (WDFY1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWB7 / WDFY1_HUMAN
Protein Name WD repeat and FYVE domain-containing protein 1
Gene Name Name: WDFY1
Synonyms:FENS1;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWB7
DAG View
PRO Name WD repeat and FYVE domain-containing protein 1 (human)
Definition A WD repeat and FYVE domain-containing protein 1 that is encoded in the genome of human.
Short Label hWDFY1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWB7 (WDFY1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
T41 Phosphorylation PhosphoSitePlus
R46 Methylation PhosphoSitePlus
C249 Methylation IEDB 31844290
T306 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
S408 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T306 A306 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S408 F408 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]