Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWB6 / TEX14_HUMAN
Protein Name Inactive serine/threonine-protein kinase TEX14
Gene Name Name: TEX14
Synonyms:SGK307;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWB6
DAG View
PRO Name inactive serine/threonine-protein kinase TEX14 (human)
Definition A testis-expressed protein 14 that is encoded in the genome of human.
Short Label hTEX14
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWB6 (TEX14) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y36 Phosphorylation PhosphoSitePlus
Y206 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
S437 Phosphorylation P53350 (PLK1) PhosphoSitePlus 22405274
Y508 Phosphorylation PhosphoSitePlus
K511 Acetylation PhosphoSitePlus
K515 Acetylation PhosphoSitePlus
T618 Phosphorylation P06493 (CDK1) PhosphoSitePlus 22405274
T727 Phosphorylation P06493 (CDK1) PhosphoSitePlus 22405274
T728 Phosphorylation P06493 (CDK1) PhosphoSitePlus 22405274
K877 Acetylation PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus
K925 Acetylation PhosphoSitePlus
K935 Acetylation PhosphoSitePlus
K935 Sumoylation PhosphoSitePlus
Y1187 Phosphorylation PhosphoSitePlus
S1215 Phosphorylation PhosphoSitePlus
Y1226 Phosphorylation PhosphoSitePlus
T1277 Phosphorylation PhosphoSitePlus
S1280 Phosphorylation PhosphoSitePlus
S1305 Phosphorylation PhosphoSitePlus
S1384 Phosphorylation PhosphoSitePlus
S1385 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y206 C206 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S284 I284 Biomuta DOID:1909 / melanoma [ cosmic ]
S284 N284 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K515 N515 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
T727 P727 Biomuta DOID:4159 / skin cancer [ icgc ]
T727 M727 Biomuta DOID:1793 / pancreatic cancer [ tcga ] DOID:363 / uterine cancer [ tcga ]
S1384 T1384 Biomuta DOID:10534 / stomach cancer [ icgc ]