iPTMnet Report for Q8IWA5 (SLC44A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IWA5 / CTL2_HUMAN
Protein Name Choline transporter-like protein 2
Gene Name Name: SLC44A2
Synonyms:CTL2;ORFNames:PSEC0210;
Organism Homo sapiens (Human)

PRO ID PR:Q8IWA5
DAG View
PRO Name choline transporter-like protein 2 (human)
Definition A choline transporter-like protein 2 that is encoded in the genome of human.
Short Label hSLC44A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IWA5 (SLC44A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y8 Phosphorylation PhosphoSitePlus
Y9 Phosphorylation PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus   UniProt 23186163
K17 Ubiquitination PhosphoSitePlus
Y18 Phosphorylation PhosphoSitePlus
T21 Phosphorylation PhosphoSitePlus
Y27 Phosphorylation PhosphoSitePlus
K115 Acetylation PhosphoSitePlus
Y120 Phosphorylation PhosphoSitePlus
N187 N-Glycosylation GlyGen   UniProt 19349973, 19159218, 24190977
K199 Ubiquitination PhosphoSitePlus
N200 N-Glycosylation GlyGen   UniProt 29741879, 24190977, 19159218, ...19349973
T202 O-Glycosylation GlyGen 35289036, 28510447
T202 Phosphorylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
T303 Phosphorylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
N417 N-Glycosylation GlyGen 29741879, 24190977
K481 Ubiquitination PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
K693 Ubiquitination PhosphoSitePlus
K698 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T21 Phosphorylation HPRD 19651622
Site PTM Type PTM Enzyme Score Source PMID
T12 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T12 M12 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T14 M14 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y18 * Biomuta DOID:3571 / liver cancer [ cosmic ]
Y27 C27 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T303 M303 Biomuta DOID:4159 / skin cancer [ cosmic ]
N417 S417 Biomuta DOID:1324 / lung cancer [ cosmic ]
S492 T492 Biomuta DOID:2531 / hematologic cancer [ cosmic ]