iPTMnet Report for Q8IW93 (ARHGEF19)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IW93 / ARHGJ_HUMAN
Protein Name Rho guanine nucleotide exchange factor 19
Gene Name Name: ARHGEF19
Organism Homo sapiens (Human)

PRO ID PR:Q8IW93
DAG View
PRO Name Rho guanine nucleotide exchange factor 19 (human)
Definition A Rho guanine nucleotide exchange factor 19 that is encoded in the genome of human.
Short Label hARHGEF19
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IW93 (ARHGEF19) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S66 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
K423 Acetylation PhosphoSitePlus
K428 Acetylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
T533 Phosphorylation PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus
T544 Phosphorylation PhosphoSitePlus
K551 Methylation PhosphoSitePlus
K763 Ubiquitination PhosphoSitePlus
K796 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S66 F66 Biomuta DOID:4159 / skin cancer [ cosmic ]
S197 L197 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K428 N428 Biomuta DOID:11054 / urinary bladder cancer [ icgc ]
K551 R551 Biomuta DOID:1324 / lung cancer [ cosmic ]