iPTMnet Report for Q8IW52 (SLITRK4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IW52 / SLIK4_HUMAN
Protein Name SLIT and NTRK-like protein 4 precursor
Gene Name Name: SLITRK4
Organism Homo sapiens (Human)

PRO ID PR:Q8IW52
DAG View
PRO Name SLIT and NTRK-like protein 4 (human)
Definition A SLIT and NTRK-like protein 4 that is encoded in the genome of human.
Short Label hSLITRK4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IW52 (SLITRK4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T301 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T306 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T307 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T334 O-Glycosylation GlyGen 30459171
K381 Acetylation PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus
T736 Phosphorylation PhosphoSitePlus
S741 Phosphorylation HPRD   PhosphoSitePlus 19651622
T742 Phosphorylation HPRD   PhosphoSitePlus 19651622
S755 Phosphorylation PhosphoSitePlus
Y769 Phosphorylation PhosphoSitePlus
K792 Methylation PhosphoSitePlus
K801 Methylation PhosphoSitePlus
Y811 Phosphorylation PhosphoSitePlus
Y824 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T307 A307 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T307 K307 Biomuta DOID:1324 / lung cancer [ cosmic ]
K381 E381 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K381 N381 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S663 Y663 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T736 I736 Biomuta DOID:1324 / lung cancer [ cosmic ]
T736 N736 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S741 I741 Biomuta DOID:363 / uterine cancer [ icgc ]
S755 C755 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K801 N801 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y824 * Biomuta DOID:1612 / breast cancer [ cosmic ]