Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8IVP5 / FUND1_HUMAN
Protein Name FUN14 domain-containing protein 1
Gene Name Name: FUNDC1
Organism Homo sapiens (Human)

DAG View
PRO Name FUN14 domain-containing protein 1 (human)
Definition A FUN14 domain-containing protein 1 that is encoded in the genome of human.
Short Label hFUNDC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8IVP5 (FUNDC1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Y11 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S13 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18452278, 19651622, 18669648, ...19690332, 27757847
S17 Phosphorylation PhosphoSitePlus   RLIMS-P 27757847
Y18 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 27653272, 22267086, 27757847
S40 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q8IVP5 (FUNDC1) S13 Q9GZQ8 (MAP1LC3B) unknown eFIP 27757847

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y11 D11 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S41 L41 Biomuta DOID:363 / uterine cancer [ tcga ]
S41 * Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]