iPTMnet Report for Q8IVP5 (FUNDC1)
Protein Information
| UniProt AC / UniProt ID | Q8IVP5 / FUND1_HUMAN |
| Protein Name | FUN14 domain-containing protein 1 |
| Gene Name | Name: FUNDC1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8IVP5 |
| PRO Name | FUN14 domain-containing protein 1 (human) |
| Definition | A FUN14 domain-containing protein 1 that is encoded in the genome of human. |
| Short Label | hFUNDC1 |
| Category | organism-gene |
DAG ViewQ8IVP5 (FUNDC1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y11 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648 | ||
| S13 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 18452278, 19651622, 18669648, ... | ||
| S17 | Phosphorylation | O75385 (ULK1) | score4 | PhosphoSitePlus RLIMS-P Signor | 24671035, 27757847, 36425056 | |
| Y18 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 27653272, 22267086, 27757847 | ||
| S40 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S41 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K119 | Ubiquitination | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q8IVP5 (FUNDC1) | S13 | Q9GZQ8 (MAP1LC3B) | unknown | eFIP | 27757847 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y11 | D11 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S41 | L41 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S41 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] |
