Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IVH8 / M4K3_HUMAN
Protein Name Mitogen-activated protein kinase kinase kinase kinase 3
Gene Name Name: MAP4K3
Synonyms:RAB8IPL1;
Organism Homo sapiens (Human)

PRO ID PR:Q8IVH8
DAG View
PRO Name mitogen-activated protein kinase kinase kinase kinase 3 (human)
Definition A mitogen-activated protein kinase kinase kinase kinase 3 that is encoded in the genome of human.
Short Label hMAP4K3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IVH8 (MAP4K3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378, 22223895
S24 Phosphorylation PhosphoSitePlus
T26 Phosphorylation PhosphoSitePlus
Y27 Phosphorylation PhosphoSitePlus
Y31 Phosphorylation PhosphoSitePlus
T145 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
S170 Phosphorylation Q8IVH8 (MAP4K3) PhosphoSitePlus   RLIMS-P   Signor 20227368
S280 Phosphorylation PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
Y366 Phosphorylation PhosphoSitePlus
Y367 Phosphorylation PhosphoSitePlus
Y379 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus   UniProt 19369195
S422 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
K530 Acetylation PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
T539 Phosphorylation PhosphoSitePlus
K541 Acetylation PhosphoSitePlus
S616 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S618 Phosphorylation PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus
Y735 Phosphorylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
S893 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S661 Phosphorylation HPRD 18691976
Site PTM Type PTM Enzyme Score Source PMID
Y366 Phosphorylation PhosphoSitePlus


Q8IVH8 (MAP4K3) as PTM Enzyme



Substrate Site Score Source PMID
Q04759 (PRKCQ) T538 neXtProt   PhosphoSitePlus   Signor 21983831
Q8IVH8 (MAP4K3) S170 PhosphoSitePlus   Signor 20227368