iPTMnet Report for Q8IVB4 (SLC9A9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IVB4 / SL9A9_HUMAN
Protein Name Sodium/hydrogen exchanger 9
Gene Name Name: SLC9A9
Synonyms:NHE9;ORFNames:Nbla00118;
Organism Homo sapiens (Human)

PRO ID PR:Q8IVB4
DAG View
PRO Name sodium/hydrogen exchanger 9 (human)
Definition A sodium/hydrogen exchanger 9 that is encoded in the genome of human.
Short Label hSLC9A9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IVB4 (SLC9A9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N96 N-Glycosylation GlyGen   UniProt 19159218
S355 Phosphorylation PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
Y530 Phosphorylation PhosphoSitePlus
Y591 Phosphorylation PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
T615 Phosphorylation PhosphoSitePlus
Y622 Phosphorylation HPRD   PhosphoSitePlus 19901323
Y631 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N96 Y96 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S355 L355 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
Y530 H530 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T615 M615 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
Y631 * Biomuta DOID:1324 / lung cancer [ cosmic ]