Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IV48 / ERI1_HUMAN
Protein Name 3'-5' exoribonuclease 1
Gene Name Name: ERI1
Synonyms:3'EXO,THEX1;
Organism Homo sapiens (Human)

PRO ID PR:Q8IV48
DAG View
PRO Name 3'-5' exoribonuclease 1 (human)
Definition A 3'-5' exoribonuclease 1 that is encoded in the genome of human.
Short Label hERI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IV48 (ERI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
K49 Sumoylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
K52 Sumoylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus   UniProt 23186163
S62 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
Y66 Phosphorylation PhosphoSitePlus
K67 Acetylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K81 Sumoylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K99 Acetylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K49 R49 Biomuta DOID:1324 / lung cancer [ cosmic ]
K87 N87 Biomuta DOID:1115 / sarcoma [ tcga ]
K300 E300 Biomuta DOID:1612 / breast cancer [ tcga ]