iPTMnet Report for Q8IV01 (SYT12)
Protein Information
| UniProt AC / UniProt ID | Q8IV01 / SYT12_HUMAN |
| Protein Name | Synaptotagmin-12 |
| Gene Name | Name: SYT12 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8IV01 |
| PRO Name | synaptotagmin-12 (human) |
| Definition | A synaptotagmin-12 that is encoded in the genome of human. |
| Short Label | hSYT12 |
| Category | organism-gene |
DAG ViewQ8IV01 (SYT12) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K65 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S97 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 17190793 | ||
| S108 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T127 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S206 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K316 | Acetylation | score1 | PhosphoSitePlus | |||
| K316 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K336 | Acetylation | score1 | PhosphoSitePlus | |||
| K337 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K65 | N65 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| T127 | I127 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S206 | Y206 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K336 | T336 | Biomuta | [ cosmic ] | |
| K337 | N337 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
