Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8IUW5 / RELL1_HUMAN
Protein Name RELT-like protein 1 precursor
Gene Name Name: RELL1
Organism Homo sapiens (Human)

DAG View
PRO Name RELT-like protein 1 (human)
Definition A RELT-like protein 1 that is encoded in the genome of human.
Short Label hRELL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8IUW5 (RELL1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K103 Ubiquitination PhosphoSitePlus
S109 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 18669648, 20068231
S114 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
T116 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
S157 Phosphorylation HPRD   PhosphoSitePlus 18669648, 20068231
S161 Phosphorylation HPRD   PhosphoSitePlus 20068231
S166 Phosphorylation HPRD   PhosphoSitePlus 18669648
T170 Phosphorylation PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
K240 Methylation PhosphoSitePlus
S244 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648
S247 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648
T253 Phosphorylation PhosphoSitePlus
T261 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus 22028470
K264 Ubiquitination PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K103 E103 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
K126 T126 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S157 R157 Biomuta DOID:3571 / liver cancer [ icgc ]
S247 P247 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K264 N264 Biomuta DOID:1324 / lung cancer [ cosmic ]