iPTMnet Report for Q8IUR6 (CREBRF)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IUR6 / CRERF_HUMAN
Protein Name CREB3 regulatory factor
Gene Name Name: CREBRF
Synonyms:C5orf41;
Organism Homo sapiens (Human)

PRO ID PR:Q8IUR6
DAG View
PRO Name CREB3 regulatory factor (human)
Definition A CREB3 regulatory factor that is encoded in the genome of human.
Short Label hCREBRF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IUR6 (CREBRF) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C95 Methylation IEDB 31844290
T102 Phosphorylation PhosphoSitePlus
T112 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
K175 Acetylation PhosphoSitePlus
C186 Methylation IEDB 31844290
T287 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus
T421 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
T513 Phosphorylation PhosphoSitePlus
T636 O-Glycosylation GlyGen 29351928
S637 O-Glycosylation GlyGen 29351928


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C95 W95 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K175 T175 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S425 L425 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S425 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]