iPTMnet Report for Q8IUH8 (SPPL2C)
Protein Information
| UniProt AC / UniProt ID | Q8IUH8 / SPP2C_HUMAN |
| Protein Name | Signal peptide peptidase-like 2C precursor |
| Gene Name | Name: SPPL2C Synonyms:IMP5; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8IUH8 |
| PRO Name | signal peptide peptidase-like 2C (human) |
| Definition | A signal peptide peptidase-like 2C that is encoded in the genome of human. |
| Short Label | hSPPL2C |
| Category | organism-gene |
Q8IUH8 (SPPL2C) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T93 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N100 | N-Glycosylation | score3 | GlyGen UniProt | 15385547 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S17 | N17 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S85 | R85 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| N100 | S100 | Biomuta | [ cosmic ] |
DAG View