iPTMnet Report for Q8IUH5 (ZDHHC17)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IUH5 / ZDH17_HUMAN
Protein Name Palmitoyltransferase ZDHHC17
Gene Name Name: ZDHHC17
Synonyms:HIP14;ORFNames:HSPC294;
Organism Homo sapiens (Human)

PRO ID PR:Q8IUH5
DAG View
PRO Name palmitoyltransferase ZDHHC17 (human)
Definition A palmitoyltransferase ZDHHC17 that is encoded in the genome of human.
Short Label hZDHHC17
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IUH5 (ZDHHC17) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y39 Phosphorylation PhosphoSitePlus
Y43 Phosphorylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
Y56 Phosphorylation PhosphoSitePlus
Y67 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Y81 Phosphorylation PhosphoSitePlus
R84 Methylation PhosphoSitePlus
T192 Phosphorylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
Y286 Phosphorylation PhosphoSitePlus
K296 Methylation PhosphoSitePlus
K299 Methylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
K462 Acetylation PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus
Y503 Phosphorylation PhosphoSitePlus
Y629 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R84 W84 Biomuta DOID:363 / uterine cancer [ icgc ]
R84 Q84 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S346 L346 Biomuta DOID:4159 / skin cancer [ cosmic ]
S346 * Biomuta DOID:363 / uterine cancer [ cosmic ]