iPTMnet Report for Q8IUF8 (RIOX2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IUF8 / RIOX2_HUMAN
Protein Name Ribosomal oxygenase 2
Gene Name Name: RIOX2
Synonyms:MDIG;
Organism Homo sapiens (Human)

PRO ID PR:Q8IUF8
DAG View
PRO Name ribosomal oxygenase 2 (human)
Definition A ribosomal oxygenase 2 that is encoded in the genome of human.
Short Label hRIOX2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IUF8 (RIOX2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K12 Acetylation PhosphoSitePlus
K20 Acetylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
K50 Sumoylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K82 Methylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K87 Methylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
C156 Methylation IEDB 31844290
S210 Phosphorylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus   UniProt 20068231
R318 Methylation PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
S327 O-Glycosylation GlyGen 30379171, 34019948
K331 Ubiquitination PhosphoSitePlus
K332 Acetylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
K356 Acetylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S309 Phosphorylation HPRD 20068231
S327 Phosphorylation HPRD 20068231
S328 Phosphorylation HPRD 20068231
Y342 Phosphorylation HPRD 20068231
S351 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S308 Phosphorylation HPRD 20068231
S326 Phosphorylation HPRD 20068231
S327 Phosphorylation HPRD 20068231
Y341 Phosphorylation HPRD 20068231
S350 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K20 E20 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S210 N210 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R318 W318 Biomuta DOID:1612 / breast cancer [ cosmic ]
S327 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S328 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K332 N332 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K439 R439 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]