iPTMnet Report for Q8IUF1 (ZNG1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IUF1 / ZNG1B_HUMAN
Protein Name Zinc-regulated GTPase metalloprotein activator 1B
Gene Name Name: ZNG1B
Synonyms:CBWD2;
Organism Homo sapiens (Human)

PRO ID PR:Q8IUF1
DAG View
PRO Name zinc-regulated GTPase metalloprotein activator 1B (human)
Definition A zinc-regulated GTPase metalloprotein activator 1B that is encoded in the genome of human.
Short Label hZNG1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IUF1 (ZNG1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
Y97 Phosphorylation PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K204 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 C7 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K41 N41 Biomuta DOID:363 / uterine cancer [ icgc ]
K126 R126 Biomuta DOID:1324 / lung cancer [ cosmic ]
K126 N126 Biomuta DOID:363 / uterine cancer [ icgc ]
K214 E214 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K214 N214 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
K301 N301 Biomuta DOID:363 / uterine cancer [ icgc ]