Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IUD6 / RN135_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF135
Gene Name Name: RNF135
ORFNames:L13;
Organism Homo sapiens (Human)

PRO ID PR:Q8IUD6
DAG View
PRO Name E3 ubiquitin-protein ligase RNF135 (human)
Definition An E3 ubiquitin-protein ligase RNF135 that is encoded in the genome of human.
Short Label hRNF135
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IUD6 (RNF135) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T76 Phosphorylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
S190 O-Glycosylation GlyGen 30059200, 35254053
K196 Ubiquitination PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
S278 O-Glycosylation GlyGen 30059200, 35254053
Site PTM Type PTM Enzyme Score Source PMID
S228 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S159 L159 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K196 R196 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]