iPTMnet Report for Q8IUC4 (RHPN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IUC4 / RHPN2_HUMAN
Protein Name Rhophilin-2
Gene Name Name: RHPN2
Organism Homo sapiens (Human)

PRO ID PR:Q8IUC4
DAG View
PRO Name rhophilin-2 (human)
Definition A rhophilin-2 that is encoded in the genome of human.
Short Label hRHPN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IUC4 (RHPN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y20 Phosphorylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
T31 Phosphorylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
S423 Phosphorylation PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
K498 Ubiquitination PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
S596 Phosphorylation PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
K603 Ubiquitination PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
T606 Phosphorylation PhosphoSitePlus
Y607 Phosphorylation PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
T614 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
S639 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S642 Phosphorylation PhosphoSitePlus
T645 Phosphorylation PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
K651 Methylation PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus
T655 Phosphorylation PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T606 Phosphorylation HPRD 19664994
S639 Phosphorylation HPRD 18669648
S652 Phosphorylation HPRD 20166139
S654 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y20 F20 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K23 R23 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y269 * Biomuta DOID:3571 / liver cancer [ cosmic ]
T614 M614 Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]