iPTMnet Report for Q8HWS3 (RFX6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8HWS3 / RFX6_HUMAN
Protein Name DNA-binding protein RFX6
Gene Name Name: RFX6
Synonyms:RFXDC1;
Organism Homo sapiens (Human)

PRO ID PR:Q8HWS3
DAG View
PRO Name DNA-binding protein RFX6 (human)
Definition A DNA-binding protein RFX6 that is encoded in the genome of human.
Short Label hRFX6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8HWS3 (RFX6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation PhosphoSitePlus
K115 Acetylation PhosphoSitePlus
K117 Acetylation PhosphoSitePlus
K118 Acetylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
Y208 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
T511 Phosphorylation PhosphoSitePlus
Y531 Phosphorylation PhosphoSitePlus
T538 Phosphorylation PhosphoSitePlus
S827 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K115 N115 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S201 T201 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S206 F206 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S217 F217 Biomuta DOID:4159 / skin cancer [ cosmic ]
T511 N511 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]