iPTMnet Report for Q8CFH6 (Sik2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8CFH6 / SIK2_MOUSE
Protein Name Serine/threonine-protein kinase SIK2
Gene Name Name: Sik2
Synonyms:Snf1lk2;
Organism Mus musculus (Mouse)

PRO ID PR:Q8CFH6
DAG View
PRO Name serine/threonine-protein kinase SIK2 (mouse)
Definition A serine/threonine-protein kinase SIK2 that is encoded in the genome of mouse.
Short Label mSIK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8CFH6 (Sik2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T175 Phosphorylation UniProt 16817901
S342 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus   RLIMS-P 25088745
S358 Phosphorylation P31750 (Akt1) , Q60823 (Akt2) PhosphoSitePlus   RLIMS-P   UniProt 29211348, 30546087, 25088745, ...17805301
T359 Phosphorylation PhosphoSitePlus
T484 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 29211348, 21220102, 25088745
S486 Phosphorylation PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
S532 Phosphorylation PhosphoSitePlus   UniProt 21183079
S534 Phosphorylation PhosphoSitePlus   UniProt 21183079
S545 Phosphorylation PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
S587 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21183079, 19351809, 32457359, ...30030465
T589 Phosphorylation PhosphoSitePlus
S590 Phosphorylation PhosphoSitePlus
S707 O-Glycosylation GlyGen 32848054


Q8CFH6 (Sik2) as PTM Enzyme



Substrate Site Score Source PMID
Q3U182 (Crtc2) S171 PhosphoSitePlus 17805301