Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8BSK8 / KS6B1_MOUSE
Protein Name Ribosomal protein S6 kinase beta-1
Gene Name Name: Rps6kb1
Organism Mus musculus (Mouse)

DAG View
PRO Name ribosomal protein S6 kinase beta-1 (mouse)
Definition A ribosomal protein S6 kinase beta-1 that is encoded in the genome of mouse.
Short Label mRPS6KB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8BSK8 (Rps6kb1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S53 Phosphorylation Q9ES70 (Nek6) phospho.ELM 12023960
K104 Ubiquitination PhosphoSitePlus
K123 Acetylation PhosphoSitePlus
K126 Acetylation PhosphoSitePlus
T140 Phosphorylation PhosphoSitePlus
R217 Methylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
T248 Phosphorylation PhosphoSitePlus
T250 Phosphorylation PhosphoSitePlus
T252 Phosphorylation phospho.ELM   PhosphoSitePlus 18347057, 17141160
T256 Phosphorylation PhosphoSitePlus
T390 Phosphorylation phospho.ELM   PhosphoSitePlus 15799971
S394 Phosphorylation Q9JLN9 (Mtor) , Q9ES70 (Nek6) phospho.ELM   PhosphoSitePlus   Signor 12023960, 12782654
S398 Phosphorylation Q9ES70 (Nek6) phospho.ELM 12023960
S403 Phosphorylation Q9ES70 (Nek6) phospho.ELM 12023960
T412 Phosphorylation Q9ES70 (Nek6) , Q9JLN9 (Mtor) phospho.ELM   PhosphoSitePlus   Signor 12023960, 12782654, 11516946, ...17141160, 17510057
S427 Phosphorylation PhosphoSitePlus
S434 Phosphorylation Q9JLN9 (Mtor) PhosphoSitePlus   Signor 12782654
S441 Phosphorylation PhosphoSitePlus
T444 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus   UniProt 21183079
S452 Phosphorylation PhosphoSitePlus   UniProt 21183079
T470 Phosphorylation phospho.ELM 7489717
S489 O-Glycosylation PhosphoSitePlus
K507 Acetylation PhosphoSitePlus
K508 Acetylation PhosphoSitePlus
K516 Acetylation PhosphoSitePlus

Q8BSK8 (Rps6kb1) as PTM Enzyme

Substrate Site Score Source PMID
P23804 (Mdm2) S163 PhosphoSitePlus 20657550
P27699 (Crem) S133 PhosphoSitePlus 7923380
P35569 (Irs1) S302 Signor 15306821
P35569 (Irs1) S522 Signor 18498745
P35569 (Irs1) S632 Signor 15306821
P35569 (Irs1) S635 Signor 18498745, 15306821
P35569 (Irs1) S731 Signor 15306821
P35569 (Irs1) S1097 Signor 15306821
P62754 (Rps6) S235 PhosphoSitePlus   Signor 15060135, 15809305
P62754 (Rps6) S236 PhosphoSitePlus   Signor 15060135, 15809305
P80314 (Cct2) S260 PhosphoSitePlus 21440620
Q64364 (Cdkn2a) S71 PhosphoSitePlus 26240281
Q9WTK7 (Stk11) S431 PhosphoSitePlus 11297520
Q9WV60 (Gsk3b) S9 PhosphoSitePlus 17052453

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q61037 (Tsc2) S939 Q8BSK8 (Rps6kb1) unknown eFIP 20412061