Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86Z20 / CC125_HUMAN
Protein Name Coiled-coil domain-containing protein 125
Gene Name Name: CCDC125
Synonyms:KENAE;
Organism Homo sapiens (Human)

PRO ID PR:Q86Z20
DAG View
PRO Name coiled-coil domain-containing protein 125 (human)
Definition A coiled-coil domain-containing protein 125 that is encoded in the genome of human.
Short Label hCCDC125
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86Z20 (CCDC125) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
K156 Acetylation PhosphoSitePlus
T168 O-Glycosylation GlyGen 31492838
T168 Phosphorylation PhosphoSitePlus
S174 O-Glycosylation GlyGen 31492838
K203 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
K353 Methylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
S502 Phosphorylation phospho.ELM 18669648
S504 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S502 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S48 F48 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S48 C48 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K203 E203 Biomuta DOID:363 / uterine cancer [ icgc ]
K252 N252 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K364 I364 Biomuta DOID:4159 / skin cancer [ cosmic ]