iPTMnet Report for Q86Z14 (KLB)
Protein Information
| UniProt AC / UniProt ID | Q86Z14 / KLOTB_HUMAN |
| Protein Name | Beta-klotho |
| Gene Name | Name: KLB |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q86Z14 |
| PRO Name | beta-klotho (human) |
| Definition | A beta-klotho that is encoded in the genome of human. |
| Short Label | hKLB |
| Category | organism-gene |
DAG ViewQ86Z14 (KLB) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N391 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| K488 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K491 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y880 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y886 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y906 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y910 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y918 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K488 | T488 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y880 | S880 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y886 | N886 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y910 | F910 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
