iPTMnet Report for Q86YZ3 (HRNR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86YZ3 / HORN_HUMAN
Protein Name Hornerin
Gene Name Name: HRNR
Synonyms:S100A18;
Organism Homo sapiens (Human)

PRO ID PR:Q86YZ3
DAG View
PRO Name hornerin (human)
Definition A hornerin that is encoded in the genome of human.
Short Label hHRNR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86YZ3 (HRNR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S97 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
Y283 Phosphorylation PhosphoSitePlus
S293 O-Glycosylation GlyGen 31061102
S293 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S306 Phosphorylation HPRD   PhosphoSitePlus 20068231
S308 Phosphorylation HPRD 20068231
S417 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
S423 O-Glycosylation GlyGen 31061102
T444 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
Y517 Phosphorylation PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
Y649 Phosphorylation PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus
S656 Phosphorylation PhosphoSitePlus
S659 Phosphorylation PhosphoSitePlus   UniProt 24275569
S661 Phosphorylation PhosphoSitePlus   UniProt 24275569
S731 Phosphorylation PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
S737 Phosphorylation PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus
S763 Phosphorylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus
S772 Phosphorylation PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
S777 Phosphorylation PhosphoSitePlus
S846 Phosphorylation PhosphoSitePlus
T847 Phosphorylation PhosphoSitePlus
S851 Phosphorylation PhosphoSitePlus
S878 Phosphorylation PhosphoSitePlus
S885 Phosphorylation HPRD   PhosphoSitePlus 20068231
S887 Phosphorylation HPRD   PhosphoSitePlus 20068231
S890 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
S898 Phosphorylation PhosphoSitePlus
S900 O-Glycosylation GlyGen 31061102
S903 Phosphorylation PhosphoSitePlus
S905 Phosphorylation PhosphoSitePlus
S911 Phosphorylation PhosphoSitePlus
S913 Phosphorylation PhosphoSitePlus
S919 Phosphorylation PhosphoSitePlus
S962 Phosphorylation PhosphoSitePlus
S967 Phosphorylation PhosphoSitePlus
S968 Phosphorylation PhosphoSitePlus
S975 Phosphorylation PhosphoSitePlus
S976 Phosphorylation PhosphoSitePlus
Y983 Phosphorylation PhosphoSitePlus
S988 Phosphorylation PhosphoSitePlus
S990 Phosphorylation PhosphoSitePlus
S993 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1001 Phosphorylation PhosphoSitePlus
S1003 Phosphorylation PhosphoSitePlus
S1006 Phosphorylation PhosphoSitePlus
S1008 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1010 Phosphorylation PhosphoSitePlus
R1028 Methylation PhosphoSitePlus
R1037 Methylation PhosphoSitePlus
S1048 Phosphorylation PhosphoSitePlus
S1110 Phosphorylation PhosphoSitePlus
S1113 Phosphorylation PhosphoSitePlus
Y1115 Phosphorylation PhosphoSitePlus
S1120 Phosphorylation PhosphoSitePlus
S1125 Phosphorylation PhosphoSitePlus
S1138 Phosphorylation PhosphoSitePlus
S1140 Phosphorylation PhosphoSitePlus
S1154 Phosphorylation PhosphoSitePlus
S1159 Phosphorylation PhosphoSitePlus
S1172 Phosphorylation PhosphoSitePlus
Y1193 Phosphorylation PhosphoSitePlus
S1198 Phosphorylation PhosphoSitePlus
S1203 Phosphorylation PhosphoSitePlus
S1204 Phosphorylation PhosphoSitePlus
S1212 Phosphorylation PhosphoSitePlus
S1213 Phosphorylation PhosphoSitePlus
Y1219 Phosphorylation PhosphoSitePlus
S1224 Phosphorylation PhosphoSitePlus
S1226 Phosphorylation PhosphoSitePlus
S1229 Phosphorylation PhosphoSitePlus
S1230 Phosphorylation PhosphoSitePlus
S1237 Phosphorylation PhosphoSitePlus
S1239 Phosphorylation PhosphoSitePlus
S1242 Phosphorylation PhosphoSitePlus
S1244 Phosphorylation PhosphoSitePlus
Y1274 Phosphorylation PhosphoSitePlus
S1276 Phosphorylation PhosphoSitePlus
S1344 Phosphorylation PhosphoSitePlus
S1347 Phosphorylation PhosphoSitePlus
Y1349 Phosphorylation PhosphoSitePlus
S1367 Phosphorylation PhosphoSitePlus
S1432 Phosphorylation PhosphoSitePlus
S1437 Phosphorylation PhosphoSitePlus
S1438 Phosphorylation PhosphoSitePlus
S1445 Phosphorylation PhosphoSitePlus
Y1453 Phosphorylation PhosphoSitePlus
S1458 Phosphorylation PhosphoSitePlus
S1460 Phosphorylation PhosphoSitePlus
S1463 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1471 Phosphorylation PhosphoSitePlus
S1473 Phosphorylation PhosphoSitePlus
S1476 Phosphorylation PhosphoSitePlus
S1478 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1480 Phosphorylation PhosphoSitePlus
S1501 Phosphorylation PhosphoSitePlus
S1580 Phosphorylation PhosphoSitePlus
S1583 Phosphorylation PhosphoSitePlus
Y1585 Phosphorylation PhosphoSitePlus
S1590 Phosphorylation PhosphoSitePlus
S1595 Phosphorylation PhosphoSitePlus
S1608 Phosphorylation PhosphoSitePlus
S1610 Phosphorylation PhosphoSitePlus
S1624 Phosphorylation PhosphoSitePlus
S1629 Phosphorylation PhosphoSitePlus
S1642 Phosphorylation PhosphoSitePlus
Y1663 Phosphorylation PhosphoSitePlus
S1668 Phosphorylation PhosphoSitePlus
S1673 Phosphorylation PhosphoSitePlus
S1674 Phosphorylation PhosphoSitePlus
S1681 Phosphorylation PhosphoSitePlus
S1682 Phosphorylation PhosphoSitePlus
S1685 Phosphorylation PhosphoSitePlus
S1686 Phosphorylation PhosphoSitePlus
Y1689 Phosphorylation PhosphoSitePlus
S1694 Phosphorylation PhosphoSitePlus
S1696 Phosphorylation PhosphoSitePlus
S1699 Phosphorylation PhosphoSitePlus
S1700 Phosphorylation PhosphoSitePlus
S1707 Phosphorylation PhosphoSitePlus
S1709 Phosphorylation PhosphoSitePlus
S1712 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1714 O-Glycosylation GlyGen 31061102
S1714 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y1744 Phosphorylation PhosphoSitePlus
S1746 Phosphorylation PhosphoSitePlus
S1824 Phosphorylation PhosphoSitePlus
S1826 Phosphorylation PhosphoSitePlus
S1829 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1831 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1837 Phosphorylation PhosphoSitePlus
S1902 Phosphorylation PhosphoSitePlus
S1907 Phosphorylation PhosphoSitePlus
S1908 Phosphorylation PhosphoSitePlus
S1915 Phosphorylation PhosphoSitePlus
Y1923 Phosphorylation PhosphoSitePlus
S1928 Phosphorylation PhosphoSitePlus
S1930 Phosphorylation PhosphoSitePlus
S1933 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1941 Phosphorylation PhosphoSitePlus
S1943 Phosphorylation PhosphoSitePlus
S1946 Phosphorylation PhosphoSitePlus
S1948 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1950 Phosphorylation PhosphoSitePlus
S1988 Phosphorylation PhosphoSitePlus
S2050 Phosphorylation PhosphoSitePlus
S2053 Phosphorylation PhosphoSitePlus
Y2055 Phosphorylation PhosphoSitePlus
S2060 Phosphorylation PhosphoSitePlus
S2065 Phosphorylation PhosphoSitePlus
S2080 Phosphorylation PhosphoSitePlus
S2138 Phosphorylation PhosphoSitePlus
S2143 Phosphorylation PhosphoSitePlus
S2144 Phosphorylation PhosphoSitePlus
Y2159 Phosphorylation PhosphoSitePlus
S2164 Phosphorylation PhosphoSitePlus
S2166 Phosphorylation PhosphoSitePlus
S2169 Phosphorylation PhosphoSitePlus
S2170 Phosphorylation PhosphoSitePlus
S2177 Phosphorylation PhosphoSitePlus
S2179 Phosphorylation PhosphoSitePlus
S2182 Phosphorylation PhosphoSitePlus
S2184 Phosphorylation PhosphoSitePlus
R2187 Methylation PhosphoSitePlus
Y2214 Phosphorylation PhosphoSitePlus
S2216 Phosphorylation PhosphoSitePlus
F2247 Phosphorylation PhosphoSitePlus
S2294 Phosphorylation PhosphoSitePlus
S2296 Phosphorylation PhosphoSitePlus
S2299 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2301 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2307 Phosphorylation PhosphoSitePlus
S2372 Phosphorylation PhosphoSitePlus
S2377 Phosphorylation PhosphoSitePlus
S2378 Phosphorylation PhosphoSitePlus
S2385 Phosphorylation PhosphoSitePlus
Y2393 Phosphorylation PhosphoSitePlus
S2398 Phosphorylation PhosphoSitePlus
S2400 Phosphorylation PhosphoSitePlus
S2403 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2411 Phosphorylation PhosphoSitePlus
S2413 Phosphorylation PhosphoSitePlus
S2416 Phosphorylation PhosphoSitePlus
S2418 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2420 Phosphorylation PhosphoSitePlus
S2441 Phosphorylation PhosphoSitePlus
S2458 Phosphorylation PhosphoSitePlus
S2520 Phosphorylation PhosphoSitePlus
S2523 Phosphorylation PhosphoSitePlus
Y2525 Phosphorylation PhosphoSitePlus
S2530 Phosphorylation PhosphoSitePlus
S2535 Phosphorylation PhosphoSitePlus
S2548 Phosphorylation PhosphoSitePlus
S2550 Phosphorylation PhosphoSitePlus
S2564 Phosphorylation PhosphoSitePlus
S2569 Phosphorylation PhosphoSitePlus
S2582 Phosphorylation PhosphoSitePlus
Y2603 Phosphorylation PhosphoSitePlus
S2608 Phosphorylation PhosphoSitePlus
S2613 Phosphorylation PhosphoSitePlus
S2614 Phosphorylation PhosphoSitePlus
S2622 Phosphorylation PhosphoSitePlus
S2623 Phosphorylation PhosphoSitePlus
Y2629 Phosphorylation PhosphoSitePlus
S2634 Phosphorylation PhosphoSitePlus
S2636 Phosphorylation PhosphoSitePlus
S2639 Phosphorylation PhosphoSitePlus
S2640 Phosphorylation PhosphoSitePlus
S2647 Phosphorylation PhosphoSitePlus
S2649 Phosphorylation PhosphoSitePlus
S2652 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2654 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2660 Phosphorylation PhosphoSitePlus
S2667 Phosphorylation PhosphoSitePlus
Y2684 Phosphorylation PhosphoSitePlus
S2686 Phosphorylation PhosphoSitePlus
S2704 Phosphorylation PhosphoSitePlus
S2705 Phosphorylation PhosphoSitePlus
S2754 Phosphorylation PhosphoSitePlus
S2757 Phosphorylation PhosphoSitePlus
Y2759 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S279 L279 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S281 F281 Biomuta DOID:4159 / skin cancer [ cosmic ]
S293 P293 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S308 N308 Biomuta DOID:3571 / liver cancer [ cosmic ]
S417 N417 Biomuta DOID:4159 / skin cancer [ cosmic ]
S418 Y418 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T444 A444 Biomuta DOID:363 / uterine cancer [ icgc ]
S516 R516 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y517 C517 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
S537 F537 Biomuta DOID:4159 / skin cancer [ cosmic ]
S542 R542 Biomuta DOID:4159 / skin cancer [ cosmic ]
S654 F654 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S656 Y656 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S656 C656 Biomuta DOID:1324 / lung cancer [ cosmic ]
S659 T659 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S736 L736 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S763 L763 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T847 M847 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S878 L878 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S890 F890 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]
S890 P890 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S900 L900 Biomuta DOID:4159 / skin cancer [ cosmic ]
S913 Y913 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S962 T962 Biomuta DOID:10283 / prostate cancer [ icgc ]
S967 P967 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S976 T976 Biomuta DOID:2998 / testicular cancer [ cosmic ]
S990 T990 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S993 Y993 Biomuta DOID:363 / uterine cancer [ icgc ]
S1001 A1001 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1001 T1001 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R1028 N1028 Biomuta DOID:4159 / skin cancer [ cosmic ]
R1028 K1028 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
R1028 G1028 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R1037 H1037 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R1037 C1037 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1113 F1113 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]
Y1115 F1115 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1471 A1471 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1642 A1642 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y1663 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1685 P1685 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y1689 C1689 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1700 L1700 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S1700 P1700 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1700 W1700 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1707 F1707 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1714 N1714 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] DOID:4362 / cervical cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
Y1744 C1744 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S1902 C1902 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S1908 Y1908 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1915 C1915 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y1923 H1923 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1930 A1930 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1930 C1930 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1930 Y1930 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1933 P1933 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1943 Y1943 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1612 / breast cancer [ cosmic ]
S1946 Y1946 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1946 P1946 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1948 R1948 Biomuta DOID:184 / bone cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S1950 G1950 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1988 F1988 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2050 N2050 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y2055 C2055 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S2138 T2138 Biomuta DOID:1324 / lung cancer [ cosmic ]
S2138 F2138 Biomuta DOID:11054 / urinary bladder cancer [ icgc ]
S2143 L2143 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S2144 Y2144 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2164 P2164 Biomuta DOID:363 / uterine cancer [ icgc ]
S2164 Y2164 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S2164 C2164 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S2166 Y2166 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S2170 L2170 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2177 F2177 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S2177 C2177 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S2184 N2184 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
R2187 Q2187 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
R2187 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y2214 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S2301 R2301 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S2398 A2398 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S2403 A2403 Biomuta DOID:363 / uterine cancer [ icgc ]
S2523 Y2523 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2623 L2623 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S2636 P2636 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S2639 Y2639 Biomuta DOID:3571 / liver cancer [ cosmic, icgc, tcga ]
S2640 A2640 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S2640 L2640 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S2640 P2640 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S2654 N2654 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S2704 Y2704 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]