Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86YW0 / PLCZ1_HUMAN
Protein Name 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
Gene Name Name: PLCZ1
Organism Homo sapiens (Human)

PRO ID PR:Q86YW0
DAG View
PRO Name 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (human)
Definition A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 that is encoded in the genome of human.
Short Label hPLCZ1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86YW0 (PLCZ1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y582 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y582 C582 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]