iPTMnet Report for Q86YV9 (HPS6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86YV9 / HPS6_HUMAN
Protein Name BLOC-2 complex member HPS6
Gene Name Name: HPS6
Organism Homo sapiens (Human)

PRO ID PR:Q86YV9
DAG View
PRO Name BLOC-2 complex member HPS6 (human)
Definition A BLOC-2 complex member HPS6 that is encoded in the genome of human.
Short Label hHPS6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86YV9 (HPS6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R61 Methylation PhosphoSitePlus
C188 Methylation IEDB 31844290
K225 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
K546 Ubiquitination PhosphoSitePlus
K555 Sumoylation PhosphoSitePlus
K646 Ubiquitination PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
K672 Ubiquitination PhosphoSitePlus
T766 Phosphorylation PhosphoSitePlus
T770 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K239 T239 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S263 F263 Biomuta DOID:4159 / skin cancer [ cosmic ]
K646 Q646 Biomuta DOID:10534 / stomach cancer [ cosmic ]