Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86YR5 / GPSM1_HUMAN
Protein Name G-protein-signaling modulator 1
Gene Name Name: GPSM1
Synonyms:AGS3;
Organism Homo sapiens (Human)

PRO ID PR:Q86YR5
DAG View
PRO Name G-protein-signaling modulator 1 (human)
Definition A G-protein-signaling modulator 1 that is encoded in the genome of human.
Short Label hGPSM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86YR5 (GPSM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K40 Ubiquitination PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
Y150 Phosphorylation PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
Y252 Phosphorylation PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
Y311 Phosphorylation PhosphoSitePlus
R325 Methylation PhosphoSitePlus
K354 Ubiquitination PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus   UniProt 19690332
R421 Methylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus   UniProt 23186163
S469 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S471 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
R479 Methylation PhosphoSitePlus
S486 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S493 Phosphorylation PhosphoSitePlus   UniProt 18669648
K504 Ubiquitination PhosphoSitePlus
C515 S-Nitrosylation dbSNO 26338901
S541 Phosphorylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus
T548 Phosphorylation PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
C670 S-Nitrosylation dbSNO 26338901


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y156 C156 Biomuta DOID:363 / uterine cancer [ icgc ]
S445 L445 Biomuta DOID:363 / uterine cancer [ tcga ]
C515 S515 Biomuta DOID:1612 / breast cancer [ tcga ]
S541 L541 Biomuta DOID:1909 / melanoma [ cosmic ]
S545 L545 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S569 I569 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]