iPTMnet Report for Q86YQ8 (CPNE8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86YQ8 / CPNE8_HUMAN
Protein Name Copine-8
Gene Name Name: CPNE8
Organism Homo sapiens (Human)

PRO ID PR:Q86YQ8
DAG View
PRO Name copine-8 (human)
Definition A copine-8 that is encoded in the genome of human.
Short Label hCPNE8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86YQ8 (CPNE8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y5 Phosphorylation PhosphoSitePlus
C48 Methylation IEDB 31844290
K58 Ubiquitination PhosphoSitePlus
T72 Phosphorylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
S260 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
S356 Phosphorylation PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
Y410 Phosphorylation PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
Y553 Phosphorylation PhosphoSitePlus
T554 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T557 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S260 Phosphorylation HPRD 17525332
Y553 Phosphorylation HPRD 20068231
T554 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S104 T104 Biomuta DOID:1612 / breast cancer [ icgc ]
K198 N198 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S356 N356 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K405 Q405 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K405 N405 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y553 F553 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y553 * Biomuta DOID:4159 / skin cancer [ cosmic ]