iPTMnet Report for Q86YA3 (ZGRF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86YA3 / ZGRF1_HUMAN
Protein Name Protein ZGRF1
Gene Name Name: ZGRF1
Synonyms:C4orf21;
Organism Homo sapiens (Human)

PRO ID PR:Q86YA3
DAG View
PRO Name protein ZGRF1 (human)
Definition A protein that is a translation product of the ZGRF1 gene in human.
Short Label hZGRF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86YA3 (ZGRF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K34 Ubiquitination PhosphoSitePlus
Y38 Phosphorylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
C44 Methylation IEDB 31844290
K51 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
K561 Ubiquitination PhosphoSitePlus
K574 Ubiquitination PhosphoSitePlus
K659 Ubiquitination PhosphoSitePlus
K770 Ubiquitination PhosphoSitePlus
K776 Ubiquitination PhosphoSitePlus
S793 Phosphorylation PhosphoSitePlus   UniProt 23186163
K808 Ubiquitination PhosphoSitePlus
K846 Ubiquitination PhosphoSitePlus
S864 Phosphorylation PhosphoSitePlus   UniProt 23186163
K870 Ubiquitination PhosphoSitePlus
S877 Phosphorylation PhosphoSitePlus
S880 Phosphorylation PhosphoSitePlus
K885 Ubiquitination PhosphoSitePlus
K924 Ubiquitination PhosphoSitePlus
K1045 Ubiquitination PhosphoSitePlus
K1145 Ubiquitination PhosphoSitePlus
K1148 Ubiquitination PhosphoSitePlus
S1177 Phosphorylation PhosphoSitePlus
T1238 Phosphorylation PhosphoSitePlus
Y1251 Phosphorylation PhosphoSitePlus
K1273 Ubiquitination PhosphoSitePlus
K1275 Ubiquitination PhosphoSitePlus
Y1331 Phosphorylation PhosphoSitePlus
K1421 Ubiquitination PhosphoSitePlus
K1434 Ubiquitination PhosphoSitePlus
K1448 Ubiquitination PhosphoSitePlus
K1461 Acetylation PhosphoSitePlus
T1462 Phosphorylation PhosphoSitePlus
K1463 Acetylation PhosphoSitePlus
Y1465 Phosphorylation PhosphoSitePlus
K1467 Acetylation PhosphoSitePlus
S1478 Phosphorylation PhosphoSitePlus
K1727 Ubiquitination PhosphoSitePlus
K1753 Ubiquitination PhosphoSitePlus
K1772 Ubiquitination PhosphoSitePlus
K1781 Ubiquitination PhosphoSitePlus
K1830 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K864 Methylation PhosphoSitePlus
K866 Methylation PhosphoSitePlus
K866 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y38 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K41 E41 Biomuta DOID:1324 / lung cancer [ cosmic ]
K183 R183 Biomuta DOID:263 / kidney cancer [ cosmic ]
K846 N846 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K870 R870 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S880 F880 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1045 R1045 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K1145 R1145 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K1275 N1275 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1448 N1448 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1478 R1478 Biomuta [ cosmic ]
S1478 C1478 Biomuta DOID:3571 / liver cancer [ icgc ]