iPTMnet Report for Q86Y97 (KMT5C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86Y97 / KMT5C_HUMAN
Protein Name Histone-lysine N-methyltransferase KMT5C
Gene Name Name: KMT5C
Synonyms:SUV420H2;ORFNames:PP7130;
Organism Homo sapiens (Human)

PRO ID PR:Q86Y97
DAG View
PRO Name histone-lysine N-methyltransferase KMT5C (human)
Definition A histone-lysine N-methyltransferase KMT5C that is encoded in the genome of human.
Short Label hKMT5C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86Y97 (KMT5C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T69 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
Y96 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
T107 Phosphorylation PhosphoSitePlus
T112 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
Y259 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
T416 Phosphorylation PhosphoSitePlus   UniProt 19690332, 20068231
T422 Phosphorylation PhosphoSitePlus   UniProt 20068231
S439 Phosphorylation PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T416 Phosphorylation HPRD 20068231
T422 Phosphorylation HPRD 20068231
S449 Phosphorylation HPRD 20068231
S452 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T69 M69 Biomuta DOID:9256 / colorectal cancer [ cosmic ]