Protein Information

Cytoscape View

UniProt AC / UniProt ID Q86Y82 / STX12_HUMAN
Protein Name Syntaxin-12
Gene Name Name: STX12
Organism Homo sapiens (Human)

DAG View
PRO Name syntaxin-12 (human)
Definition A syntaxin-12 that is encoded in the genome of human.
Short Label hSTX12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q86Y82 (STX12) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378, 22223895
S2 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
S139 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648
S142 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18578522, 23186163, 17081983, ...19651622, 18669648, 18707149, 20068231
S218 Phosphorylation HPRD   PhosphoSitePlus 20166139
S225 Phosphorylation PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
Y242 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K44 N44 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:5041 / esophageal cancer [ icgc ]
S218 I218 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S218 N218 Biomuta DOID:2531 / hematologic cancer [ icgc ]
T234 A234 Biomuta DOID:9256 / colorectal cancer [ icgc ]